Statins for Familial Hypercholesterolemia
Studies have shown that statins can reduce LDL-cholesterol by 35 to 55 percent and can reduce the risk of cardiovascular disease (CVD) by 22 percent for each 40 mg/dL (1 mmol/L)reduction in LDL cholesterol. 
Types of Statins
High Potency Statins
- Rosuvastatin (Crestor)
- Atorvastatin (Lipitor)
- Pitavastatin (Livalo)
- Simvastatin (Zocor)
- Lovastatin (Mevacor, Altoprev)
- Pravastatin (Pravachol)
- Fluvastatin (Lescol, Lescol XL)
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Who Are Recommended to Take Statins?
- People who already have atherosclerotic cardiovascular disease. This group includes people who have had heart attacks, strokes caused by blockages in a blood vessel, mini-strokes (transient ischemic attacks), peripheral artery disease, or prior surgery to open or bypass coronary arteries.
- People who have very high LDL cholesterol. This group includes adults who have LDL-cholesterol levels of 190 mg/dL (4.9 mmol/L) or higher. This group includes people with Familial Hypercholesterolemia, including children who can begin taking statins between the ages of 8-10.
- People who have diabetes. This group includes adults who have diabetes and an LDL-cholesterol between 70 and 189 mg/dL (1.8 and 4.9 mmol/L), especially if they have evidence of vascular disease.
- People who have a higher 10-year risk of heart attack. This group includes people who have an LDL- cholesterol between 70 and 189 mg/dL (1.8 and 4.9 mmol/L), and whose 10-year risk of a heart attack is 7.5 percent or higher.
Not everyone can take statins such as women who are trying to conceive, pregnant, or nursing. Talk to you doctor about other therapy options.